FDA-Approved · 65+ Years of Clinical Use

Fast-acting. Medically supervised. A proven prescription option for weight loss.

Phentermine has been used in medical weight management for decades. At Rivas, we prescribe it selectively, monitor your progress closely, and adjust your plan based on your results and tolerability.

  • Oral pill — no injections
  • Works from day one
  • $195 includes 2 weeks of medication
  • Maryland in-person visits only
phentermine hero image

HSA & FSA accepted · Pricing subject to change

PRICING

Get started with phentermine

Every visit includes a provider visit, vitals and weigh-in, and medication. No separate pharmacy trip required.

2-Week Follow-Up

From

$90

Provider visit + vitals and weigh-in + 2 weeks of medication included

  • Provider visit
  • Vitals and weigh-in
  • 2 weeks of phentermine included

Monthly Follow-Up

From

$115

Provider visit + vitals and weigh-in + 4 weeks of medication included

  • Provider visit
  • Vitals and weigh-in
  • 4 weeks of phentermine included

HSA & FSA accepted. Follow-up pricing may vary based on dose and treatment plan.  View full pricing →

HOW IT WORKS

Why phentermine works differently

Phentermine works through the central nervous system rather than the GLP-1 pathway. In plain terms, it uses a different route to help reduce appetite — which is one reason it may be a strong fit for some patients.

1

Helps reduce appetite from the start

Phentermine helps reduce hunger by increasing norepinephrine signaling in the brain. Many patients notice that eating feels more manageable early on — especially compared with options that may take longer to build over time.

2

Built for daytime appetite control

Because phentermine is a stimulant-based medication, patients often describe feeling more alert and more in control of appetite during the day. It is typically taken in the morning so its effects align with waking hours.

3

Matched to the patient, not one protocol

Phentermine is prescribed based on your medical history, current medications, prior treatment response, and tolerability. The goal is to find a dose and plan that is effective, appropriate, and sustainable under provider supervision.

Different pathway. Same goal.

Helping patients feel less hungry, eat more comfortably, and make progress with provider guidance.

Side Effects

What patients report

Phentermine is a stimulant, so side effects differ from GLP-1 medications. Most are mild, manageable, and improve as the body adjusts.

Dry mouth

COMMON

Difficulty sleeping

COMMON

Increased heart rate

COMMON

Restlessness

LESS COMMON

Constipation

LESS COMMON

Headache

LESS COMMON

Elevated blood pressure

LESS COMMON

Taking phentermine at 6 a.m. minimizes sleep disruption. Staying well-hydrated helps with dry mouth and constipation. Your provider monitors blood pressure at every visit and will adjust the dose or plan if needed.

Who should not take phentermine

Your provider evaluates cardiovascular health before prescribing. Phentermine is not appropriate for patients with uncontrolled high blood pressure, heart disease, hyperthyroidism, glaucoma, or a history of drug abuse. It is not prescribed during pregnancy or breastfeeding. Phentermine cannot be taken with MAO inhibitors or with stimulant ADHD medications such as Adderall or Ritalin.

If phentermine is not appropriate for you, your provider may recommend semaglutide or tirzepatide as an alternative.

Side Effects

What patients report

Phentermine is a stimulant, so side effects differ from GLP-1 medications. Most are mild, manageable, and improve as the body adjusts.

common

Most patients notice these early on. They typically ease within the first 1–2 weeks.

  • Dry mouth
    Staying well-hydrated helps. Your provider will give you a daily water target at your first visit — hitting it makes a real difference for this one.
  • Difficulty sleeping
    Taking phentermine at 6 a.m. lets the stimulant effect wind down well before bedtime. Timing is one of the most controllable factors.
  • Increased heart rate
    Phentermine is a stimulant — a mild rise in heart rate is expected.

LESS common

Not everyone experiences these. Mention them at your follow-up if they occur.

  • Restlessness
    Often settles within the first week. Channeling the energy into movement — even a short walk — helps many patients.
  • Constipation
    Hydration and movement usually resolve this. Your provider can advise at your follow-up if it persists.
  • Headache
    Common in the first few days as the body adjusts. Usually short-lived and improves with adequate hydration.

Monitored at every visit

  • Blood pressure
    As you lose weight, blood pressure often drops — which is good, but it can mean patients already on blood pressure medication are taking more than they now need. One such sign is dizziness when standing up quickly or bending over. Your provider checks your blood pressure at every visit to catch this early and coordinate with your other prescribers if an adjustment is needed.

    A common concern is that phentermine raises blood pressure. A 2011 study in Obesity found the opposite: blood pressure declined in phentermine-treated patients at 26 and 52 weeks, at a rate similar to untreated patients losing weight through lifestyle alone.
    Hendricks EJ et al. Obesity (Silver Spring). 2011;19(12):2351–60. n=300. Applies to patients without pre-existing cardiovascular disease. Individual results vary.

Who should not take phentermine

Phentermine is not appropriate for patients with uncontrolled high blood pressure, heart disease, untreated hyperthyroidism, or untreated glaucoma. It is not prescribed during pregnancy or breastfeeding. Phentermine cannot be taken with MAO inhibitors. We do not prescribe it if you are taking a stimulant ADHD medication such as Adderall or Ritalin.

If phentermine is not appropriate for you, your provider may recommend semaglutide or tirzepatide as an alternative.

Side effects vary by patient. This is not a complete list. Your provider reviews your individual history before prescribing and monitors your response at every follow-up.

Why Rivas Is Different

Obesity is a chronic disease. We treat it like one.

Phentermine works through the central nervous system rather than the GLP-1 pathway. In plain terms, it uses a different route to help reduce appetite — which is one reason it may be a strong fit for some patients.

  • Most primary care doctors won’t prescribe phentermine at all — a stigma left over from the fen-phen era that has nothing to do with phentermine’s actual safety record.
  • When a PCP does prescribe it, the standard is a 3-month limit — just long enough to work, not long enough to last.
  • When the prescription ends and the weight returns, patients are made to feel like they failed — they didn’t; the approach failed them.
  • Obesity doesn’t resolve when you hit goal weight, the same way hypertension doesn’t resolve when your numbers normalize — it requires ongoing management.
  • At Rivas, phentermine is prescribed as a long-term tool under medical supervision — not a temporary fix with an arbitrary expiration date.

“They didn’t fail. The system failed them.”

A 2019 study published in Obesity — the journal of The Obesity Society — analyzed nearly 14,000 adults (84% female) and found that patients who used phentermine for longer than 12 months lost significantly more weight at 6 months, one year, and two years compared to those who stopped at three months. Critically, longer-term use was not associated with any increased risk of cardiovascular events or death.

What most patients have already heard

  • “Just eat less and move more”
  • Try a Mediterranean diet
  • OTC supplements, meal replacements
  • 3-month prescription, then you’re on your own
  • Regain treated as patient failure

How Rivas treats it

  • Ongoing prescribing under medical supervision
  • Maintenance program
  • Early intervention if weight returns
  • Treated as the chronic disease it is

CLINICAL RESEARCH

Long-term phentermine produces greater weight loss

Lewis et al., Obesity, 2019  ·  ~14,000 adults, 84% female

Long-term use (>12 months)

Short-term use (≤3 months)

Average body weight lost 12% 10% 8% 6% 4% 2% 0% 6 months 1 year 2 years

6 MONTHS

2x more

weight lost

1 year

2x more

weight lost

2 years

No increased

cardiovascular risk

Chart values are approximate representations of study findings. Individual results vary. Source: Lewis KH et al. Long-term safety and effectiveness of phentermine use. Obesity. 2019.

CLINICAL RESEARCH

The longer patients stayed on phentermine, the more weight they lost

Average weight loss 0% 3% 6% 9% 12% ~4% ~7.5% ~8% 3 months Max prescribed by primary care 6 months With ongoing supervision 1 year With ongoing supervision

Lewis et al., Obesity, 2019  ·  ~14,000 adults, 84% female  ·  Long-term use group (>12 months)

Chart values are approximate representations of study findings. Individual results vary. Source: Lewis KH et al. Long-term safety and effectiveness of phentermine use. Obesity. 2019. Reflects patients without pre-existing cardiovascular disease treated under medical supervision.

A 2019 study published in Obesity — the journal of The Obesity Society — analyzed nearly 14,000 adults (84% female) and found that patients who used phentermine for longer than 12 months lost significantly more weight at 6 months, one year, and two years compared to those who stopped at three months. Critically, longer-term use was not associated with any increased risk of cardiovascular events or death.

Your Visit

What to expect at your first appointment

Most patients walk out with medication on the same visit. Here is what the appointment looks like.

1

Medical evaluation

Your provider reviews your health history, current medications, blood pressure, and weight. This determines whether phentermine is appropriate and what dose to start with

2

Leave with medication

Most patients receive their prescription at the same visit. Your provider covers dosing, timing, nutrition guidance, and what to expect in the first few days. Questions about side effects, sleep, hydration, and protein are all addressed before you leave.

3

Two-week follow-up

You return at two weeks to assess response, side effects, and progress. Individual results may vary.

Patient Guidance

How to get the most out of phentermine

Your provider will cover all of this at your first visit. Here is what to know before you start.

Take it before you begin your day

Phentermine absorbs best on an empty stomach, and taking it at the start of your waking hours means appetite suppression peaks when you need it most and fades before you sleep. Patients who take it later in their day consistently report more sleep disruption. Timing is one of the most controllable factors in your experience.

Expect energy. Use it.

Phentermine is a stimulant, and the energy is real. Patients often describe wanting to get up and move on day one. Channel it — even a daily walk materially improves outcomes. The energy window is an asset, not just a side effect to sit through.

Front-load your protein

The most common pattern: appetite suppression works all day, the patient barely eats, then the medication wears off in the evening and hunger returns hard. The fix is to eat your protein earlier — before you feel hungry — so you are not running a deficit by 8 p.m. Your provider will give you specific guidance at your first visit.

Choosing the Right Tool

Different tools. Flexible treatment strategy.

Phentermine and GLP-1 medications work through different pathways and can play different roles over the course of treatment. Some patients do well with one alone, while others may benefit from adding the second later if progress slows, appetite control changes, or a different approach is needed.

Oral Prescription

Phentermine

  • Oral medication — no injections
  • Often works early in treatment
  • Daily dosing
  • Helps reduce appetite
  • May support energy and daytime structure
  • Can be used alone or as part of a broader plan

A fit for patients who prefer pills over injections, want an earlier effect, or may benefit from a different mechanism at certain points in treatment.

Weekly Injection

Semaglutide / Tirzepatide

  • Weekly injection
  • Builds gradually over time
  • Reduces hunger and increases fullness
  • Helps address food noise for many patients
  • Often used for longer-term appetite control
  • May be paired with other tools under supervision

A fit for patients who want a longer-building medication, need sustained appetite control, or may benefit from adding a second tool later in treatment.

Can phentermine and a GLP-1 be used together?

Yes, in some cases. Some patients begin with one medication and add the second later if they hit a plateau, need stronger appetite control, or would benefit from a different mechanism. This is decided individually based on medical history, blood pressure, tolerability, and treatment response.

Individualized Care

A treatment plan tailored to you

There is no one-size-fits-all approach to medical weight loss. Some patients do well with one medication alone, while others may benefit from adding a second later or starting with both from the beginning. Your provider adjusts the plan carefully based on your response, tolerability, and goals.

0% −5% −10% −15% −20% % BODY WEIGHT CHANGE Start 2 mo 4 mo 6 mo 8 mo 10 mo 12 mo PLATEAU ~19% ~14% Second medication added Plateau breaks, progress resumes ~7% Progress stalls here Starting weight Illustrative only. Individual results vary. Your provider determines the right plan based on your response, tolerability, and clinical goals.

One medication may be enough

Many patients do well with one medication and continue making progress with regular follow-up.

A second medication may be added later

If progress slows, your provider may add a second medication to help restart momentum.

Some patients begin with both medications

For some patients, starting with both medications may be the right fit from the beginning.

Phentermine is FDA-approved and available at Maryland locations. GLP-1 medications are available at all locations, including telehealth. All treatment decisions are made by your provider.

Clinical Education

How your treatment plan may evolve over time

Phentermine and GLP-1 medications are not competing options. Depending on the patient, one may be enough, a second may be added later, or both may be appropriate from the start. A common approach is to begin with one medication and adjust over time if needed. Your provider determines this based on response, tolerability, and goals.

Treatment is individualized. Some patients stay on one medication alone, some add a second later in either direction, and some remain on both because the combination continues to feel effective and appropriate for them.

Frequently Asked Questions

Phentermine FAQ

How much does phentermine cost?

Your initial visit is $195 and includes your first two weeks of phentermine. Follow-up visits start at $90 for a two-week supply or $115 for a monthly supply — medication included in both. If your provider recommends additional appetite suppressants or combination therapy, the cost may be adjusted. HSA and FSA cards are accepted. Pricing is subject to change.

How fast does phentermine work?

Most patients notice appetite suppression the same day — within a few hours of the first dose. For patients new to phentermine, providers report seeing 7–10 pounds of loss in the first two weeks. For patients who have been on phentermine before, 3–5 pounds in the first two weeks is more typical. Individual results vary based on medical history, adherence, dose, and metabolism. Your provider will set realistic expectations at your first visit.

How long can I take phentermine?

Obesity is a chronic disease, and phentermine can be part of long-term management under medical supervision — the same way blood pressure medication is used to manage hypertension over time. A 2019 study in Obesity — the journal of The Obesity Society — analyzed nearly 14,000 adults and found that patients who used phentermine longer than 12 months lost significantly more weight at six months, one year, and two years compared to those who stopped at three months. Longer-term use was not associated with increased cardiovascular risk. At Rivas, your provider evaluates progress and blood pressure at every visit and adjusts your plan accordingly.

Is phentermine the same as Ozempic or semaglutide?

No. Phentermine and GLP-1 medications like semaglutide work through completely different mechanisms. Phentermine is a stimulant that suppresses appetite through the central nervous system. Semaglutide is a GLP-1 receptor agonist that reduces hunger by acting on gut hormone pathways. Phentermine is an oral pill; semaglutide is a weekly injection. Both are used at Rivas for ongoing weight management under medical supervision and can be used together when clinically appropriate.

Can I take phentermine with semaglutide or tirzepatide?

Yes. Combining phentermine with a GLP-1 medication is a common approach at Rivas, particularly for patients in a plateau or during the early titration period of a GLP-1 when full appetite suppression has not yet been established. Your provider monitors blood pressure and side effects closely when prescribing both medications together. This approach is evaluated individually — it is not appropriate for every patient.

Is phentermine available through Rivas telehealth?

No. Phentermine is a Schedule IV controlled substance. Federal and Maryland state regulations prohibit controlled substance prescriptions via telehealth without a prior in-person relationship, and we do not prescribe phentermine remotely under any circumstances. Phentermine is available at our Maryland clinic locations only. If you are interested in a weight loss medication that can be managed via telehealth, our providers can discuss semaglutide or tirzepatide — both of which are available through Rivas Telehealth.

Can I take phentermine on Adderall or Ritalin?

No. Rivas does not prescribe phentermine to patients currently taking stimulant ADHD medications such as Adderall (amphetamine) or Ritalin (methylphenidate). Both phentermine and these medications are central nervous system stimulants, and combining them carries significant cardiovascular risk — including elevated heart rate, increased blood pressure, and potential cardiac events. If you currently take a stimulant ADHD medication, your provider can discuss alternative weight loss options at your visit.

What brand of phentermine does Rivas carry?

We carry KVK Tech phentermine — an American-manufactured formulation widely regarded among providers for consistency and quality. The classic tablet is white with blue speckles and is taken once daily in the morning. Your provider will confirm the right formulation and dose for you at your visit.

What is phentermine 37.5?

Phentermine 37.5 refers to a common tablet strength of phentermine hydrochloride, typically taken once daily in the morning. Phentermine is also available in other strengths and in capsule form. Your provider determines the right formulation and dose based on your individual history, current medications, and prior experience with phentermine — there is no one-size-fits-all protocol.

Related Reading

Learn more

More on phentermine, weight loss medication, and what to expect — from the Rivas GLP-1 Latest News blog.

The Jumpstart You’ve Been Looking For

Phentermine available at Maryland locations only